Search for: All records

Abstract Chemical modification is a powerful strategy for tuning the electronic properties of 2D semiconductors. Here we report the electrophilic trifluoromethylation of 2D WSe₂and MoS₂under mild conditions using the reagent trifluoromethyl thianthrenium triflate (TTT). Chemical characterization and density functional theory calculations reveal that the trifluoromethyl groups bind covalently to surface chalcogen atoms as well as oxygen substitution sites. Trifluoromethylation induces p‐type doping in the underlying 2D material, enabling the modulation of charge transport and optical emission properties in WSe₂. This work introduces a versatile and efficient method for tailoring the optical and electronic properties of 2D transition metal dichalcogenides. 

Abstract Photocatalytic anticancer profile of a Ir^IIIphotocatalyst (Ir3) with strong light absorption, high turnover frequency, and excellent biocompatibility is reported.Ir3showed selective photo‐cytotoxicity against cisplatin‐ and sorafenib‐resistant cell lines while remaining dormant to normal cell lines in the dark.Ir3exhibited excellent photo‐catalytic oxidation of cellular co‐enzyme, the reduced nicotinamide adenine dinucleotide phosphate (NADPH), and amino acids via a single electron transfer mechanism. The photo‐induced intracellular redox imbalance and change in mitochondrial membrane potential resulted in necrosis and apoptosis of cancer cells. Importantly,Ir3exhibited high biocompatibility and photo‐catalytic anticancer efficiency as evident from in vivo zebrafish and mouse cancer models. To the best of our knowledge,Ir3is the first Ir^IIIbased photocatalyst with such a high biocompatibility and photocatalytic anticancer therapeutic effect.